Time flew by like a white steed. Whether it was leisure time or busy work, it could fly by without anyone noticing.
In the blink of an eye, the new year had passed. It was year 2221 of the Earth Federation.
Although school had not started yet, many of the postgraduate students had already returned to school early.
The originally deserted campus became lively again with the return of the students.
However, for the past month, Chen Chen's team of three had been working day and night. They had to work more than ten hours a day in the laboratory.
They would eat breakfast at eight in the morning and enter the laboratory at nine. Other than leaving the laboratory for lunch at noon, it would be after nine at night by the time they came out.
Sometimes, when they were too tired, Chen Chen and Wang Wei would not return to school and spend the night in the lounge.
Meanwhile, Xia Yin's work leaned toward logistics such as buying food, delivering water, and taking care of the experimental animals. It was much easier than the two of them.
Three days before school started, the last batch of mice implanted with egg cells finally gave birth to the cloned babies. The preliminary work of the experiment was considered to be successfully completed.
Therefore, Chen Chen divided the cloned mice into three groups.
The first group was the brain injury model group, which was further divided into two groups, A and B.
Among them, Team A would be treated with artificially cultivated autologous stem cells while Team B would be treated with cloned autologous stem cells. There were four mice in each of the two groups.
The second group was the spinal injury model group. Similarly, Team A would be treated with artificially cultivated autologous stem cells while Team B would be treated with cloned autologous stem cells. There were four mice in each of the two groups.
The third group had the largest number of mice, a total of twenty. They were all specially selected elderly SD rats. They were used for the experiment of rebuilding the immune system.
All the mice in this group had been cloned and had corresponding cloned stem cells.
They would be subjected to radiotherapy and chemotherapy to kill off most of the hematopoietic stem cells and mesenchymal stem cells in the body. Then, they would be injected with the cloned stem cells to see if they would regain their youth.
This was the so-called bone marrow transplant.
As for why there were so many mice in the third group?
That was because the process of radiotherapy and chemotherapy alone could kill off more than half of this batch of mice.
Radiotherapy and chemotherapy were treatment methods that used radiation and chemicals to kill off the cancer cell clusters in a certain part of the patient's body.
However, this treatment method had always been self-destructive. After all, while killing the cancer cells, the normal cells in the patient's body would also be overwhelmed.
This was also the reason why patients with chemotherapy and radiotherapy would lose their hair.
In fact, many patients with advanced cancer did not die from the spread of cancer cells, but from the chemotherapy process that destroyed the patient's body. It was a tragedy.
Since cancer was officially discovered in 1911, the war between humans and cancer has lasted for hundreds of years.
In this protracted war, humans were helpless against cancer. Then came the radiotherapy and chemotherapy, and now various targeted drugs. Little by little, they regained the lost ground of life.
The advent of bone marrow transplantation marked the first victory in the war between humans and cancer.
This kind of victory would continue to spread until one day in the future, humans would completely defeat the disease of cancer and make cancer disappear from the human population.
It was just like the smallpox back then.
Of course, not every bone marrow transplant was successful.
The success rate of bone marrow transplantation, which was currently recognized by the medical community to treat leukemia, was only 60%.
Among the 60%, half of the patients would relapse after half a year.
Therefore, bone marrow transplantation was still a thorny journey for humans to fight against disease.
If there was any mishandling in the middle of the process, resulting in the death of this batch of mice, it was equivalent to a month's worth of manpower and resources going down the drain.
After all, if the original body was gone, what was the use of these corresponding cloned stem cells?
Therefore, in order to accumulate experience in radiotherapy and chemotherapy on mice, Chen Chen deliberately used other mice to test the waters.
However, mice were different from humans. These chemotherapy methods were still too intense for the mice. Chen Chen could only guarantee a forty percent survival rate.
However, with the birth of the last batch of cloned mice, the preliminary preparations for Chen Chen's three experiments were finally completed.
Next, it was the official experimental period.
Another five days had passed and it was officially the day of the new semester.
Chen Chen and the other two submitted an application to the school to delay their return to school and continued to hole up in the laboratory day and night.
At the same time, with the use of stem cell treatment, the first and second groups began to show signs of recovery.
The third group, on the other hand, was in a bad situation. Out of the twenty SD rats, five had died. Although the remaining rats were alive, they were on the brink of death and even stopped eating.
Two days later, the chemotherapy was completely over. Some of the rats that were already on the brink of death were completely overwhelmed. Eight or nine of them died one after another, leaving only six alive.
Still, six was enough.
Chen Chen's only hope now was that two or three of these six could persevere until the end of the experiment.
In this tense atmosphere, another month and a half passed.
The three-month experimental period that was once planned was finally coming to an end.
At this moment, the three of them gathered in front of a group of mice. Everyone had an excited expression on their faces.
"Final results verified..."
Chen Chen said to the recorder, "The first brain injury model group, team A, 3 numbers, 3 survived. Degree of recovery: Number 1 is relatively better, Number 2 is significantly better, Number 3 is slightly better...
"The first brain injury model group, team B, 3 survived. Degree of recovery: Number 1 is significantly better, Number 2 is significantly better, Number 3 is significantly better.
"Summary: The treatment effect of team A using artificial stem cell cultivation is significantly inferior to team B using cloned autologous stem cells.
"The second spinal injury model group, team A, 4 numbers... Team B, 4 numbers. Same as above. Regardless of recovery speed or effect: team A is inferior to team B.
"The third experiment group, 3 survived in the end. The basic CT shows that the body functions of the experimental subjects that were originally in a state of aging have been greatly enhanced in all aspects...
"I can't believe that the three experiments were successful!"
Wang Wei patted Chen Chen's shoulder excitedly. "In other words, the cloned young stem cells are far more effective than artificially cultivated autologous stem cells?"
"Also, the third experiment group also shows that bone marrow replacement can really restore one's youth?"
Xia Yin also murmured in a low voice with a look of disbelief. "Chen Chen, we're going to be famous..."
Although Chen Chen was also smiling, his eyes were very calm. "Next, I'll be writing two papers. As mentioned before, Xia Yin will be the lead author, Brother Wei will be the second author, and I'll be the corresponding author. Is that okay?"
"No, I'm basking in the glory of the two of you. If it weren't for you, Lil Chen, the experiment wouldn't have gone so smoothly."
Wang Wei looked calm and suddenly wondered, "By the way, why are there two papers? Aren't there three experiments in three groups? "
"One of them is about the difference in the effects of artificially cultivated stem cells and cloned autologous stem cells on the human body. This paper automatically covers the first and second experiments."
Chen Chen explained, "The other paper is the experiment of bone marrow transplantation."
"That's true. It's more convincing to put the first and second groups together."
Xia Yin smiled and nodded. "What about the submission? Surely it'll be submitted to the first section? "
"Of course, between these two research results, the first one might be a little uncertain, but submitting to the second one shouldn't be a problem."
Hearing this, Xia Yin and Wang Wei cheered again.
"Which journal are you going to submit to?" Xia Yin asked.
"There are only a few top journals in the field of biology in the first section. Of course, I'll submit to Cell!"
Wang Wei answered first, "Didn't your supervisor teach you? The shorter the journal name, the more awesome it is! "
Cell, also known as Cell, was a journal about the latest research findings in the field of life sciences. It was undoubtedly the top of the top journals in the field of biology. Its impact factor had never fallen out of the top three since its inception. It could be said to be the faith of those who worked in the life sciences.
Researchers often referred to it as "CNS paper". The CNS here was the abbreviation of the top three journals, Cell, Nature, and Science. There was no one who would not be proud to publish a paper in these three journals.
You've already exceeded your reading limit for today. If you want to read more, please log in.
Login
Select text and click 'Report' to let us know about any bad translation.
