Lu Jin went to his lab bench and intercepted the alleles from Qin Yaoguang and Wen Shouyi's DNA fragments for verification and comparison.
Logically speaking, the accuracy of a DNA test could be 100% when eliminating the possibility of non-parentage.
In other words, when two people were not related by blood, it was 100% accurate.
However, to determine that two people were directly related by blood, the accuracy was only this decimal point. The nine after the decimal point could vary according to the number of alleles intercepted.
However, under normal circumstances, when the accuracy of determining that two people were directly related by blood, one could basically determine that two people were directly related by blood.
Lu Jin had tested the DNA of Qin Yaoguang and Wen Shouyi, and he had tested the full sequence.
This was not only a sequence that ordinary people could not afford, but even many people with millions of dollars might not be able to afford it. Of course, it was not a big deal for Lu Jin.
He had tested the full sequence, and the alleles he had intercepted were as diverse as possible. Therefore, the accuracy of his test of parentage was the highest, even if it was not 100%.
Before the test, he first ran electrophoresis. Simply put, it was to let the DNA double helix structure "swim" under a certain voltage. The DNA fragments with different functions "swim" at different speeds, so that different DNA fragments could be separated.
Then, the alleles were intercepted and the software was used to analyze and compare.
Lu Jin completed the entire procedure, and Gu Nianzhi watched with relish.
Although she couldn't understand the pictures and data at all.
In order to be accurate, Lu Jin spent half an hour using the software to analyze and compare the intercepted allele fragments.
Finally, he let out a long sigh. "… They really are biological mother and daughter."
Gu Nianzhi: "…"
She was a little confused by the result.
She was mentally prepared, but when the prediction was confirmed, she found it unbelievable.
"… Qin Yaoguang and Wen Shouyi?! They're really biological mother and daughter?! "Gu Nianzhi was extremely shocked." Then it must be surrogacy? But why did she put Wen Shouyi in the Qin orphanage? She even let Wen Dayou and his wife adopt her?! "
Lu Jin nodded. "Surrogacy must be the only explanation. But why did Qin Yaoguang put Wen Shouyi in the orphanage? I can only ask Qin Yaoguang. "
"… But do you think she'll tell the truth?" Gu Nianzhi said faintly, her eyes dark.
Lu Jin said very seriously, "She probably won't. But I think this is her privacy. Do you really have to ask? "
"Yes." Gu Nianzhi nodded cautiously. "This concerns the integrity of the evidence chain in court. Dad, you know Qin Yaoguang better. Can you deduce why she did this? "
When Gu Nianzhi talked about legal terms, Lu Jin's eyes were as round as Gu Nianzhi's when she heard high-energy physics terms.
He said a little dizzily, "Actually, I don't know Qin Yaoguang very well. But I've been collaborating with her for so many years, and I basically know her attitude towards genetic research. "
"What attitude?" Gu Nianzhi asked quickly.
"Genetic research is one of her specialties. She used her own egg cells to synthesize fertilized eggs and let another woman give birth to them as a surrogate. It was like catching a white mouse from a cage."
"Have you ever seen a researcher pour their feelings into a lab rat? Or do you treat a lab rat as a human? "
Gu Nianzhi pouted and muttered, "I'm also a lab rat, but Qin Yaoguang might as well throw me into an orphanage if she used me as an experiment. Why didn't she use Wen Shouyi as an experiment? "
Lu Jin's heart ached, and he didn't know how to comfort her.
In a moment of desperation, he subconsciously said, "… Maybe Wen Shouyi was the product of a failed experiment, so she wasn't used as an experiment."
Gu Nianzhi: "…"
Although she wasn't comforted, it was a good thing that her mood had miraculously improved …
Gu Nianzhi's face was still stern as she said seriously, "Looks like I'm still useful."
Lu Jin rubbed his hands awkwardly and begged for mercy, "… Nianzhi, Dad knows he was wrong …"
Gu Nianzhi was embarrassed. She stepped forward to hold Lu Jin's hand and pulled him to the sofa to sit down. She said, "Dad, I was just joking. But … "
Her eyes darted around. "You mean, Qin Yaoguang started doing genetic research on embryos a long time before I was born?"
This question could be answered.
Lu Jin said in an academic manner, "I don't have any concrete evidence, but since Wen Shouyi was born in this way, Qin Yaoguang must have done research on this."
"At that time, she didn't ask me for advice, so I didn't know that she had been doing experiments on this for a long time."
In other words, six years before Gu Nianzhi was born, Lu Jin still knew nothing about Qin Yaoguang's secret experiments.
Gu Nianzhi nodded and continued to ask curiously, "But why did she use her own egg cells and Wen Dayou's sperm as fertilized eggs to conceive an embryo? I thought she would use other people's egg cells for research. "
Lu Jin smiled and said casually, "If she already had such an experimental subject born, then it definitely wasn't the first time she had done this experiment, and it definitely wouldn't be the last."
"What do you mean?" Gu Nianzhi's eyes suddenly lit up. "Could it be that she has done a lot of research on this, and even used other people's egg cells?"
"From a scientific perspective, that's for sure."
Lu Jin patiently explained to her, "This kind of human embryo experiment has a long cycle. Usually, it takes at least seven months from fertilization to birth of the fetus, if you include premature babies."
"Normally, it would take nine months. In addition to the preparation before and after, as well as the process of screening the pregnant men and women, a year would pass."
"When an experiment takes a year to prepare to produce results, then the person doing the experiment will definitely not only do one experiment at a time. Do you understand what I mean?"
Gu Nianzhi carefully digested Lu Jin's words in her mind. After a while, she said thoughtfully, "What you mean is that doing this kind of experiment is no different from doing other biological experiments. You need to do a large number of experiments in order to screen out effective results."
"She will prepare a lot of these fertilized eggs and transplant them into the pregnant mother's stomach at the same time. She will implant them and then observe the results."
Lu Jin nodded heavily. "That's right. The failure rate of biological genetic experiments is actually quite high. Therefore, she needs to accumulate quantity and achieve qualitative change from quantitative change. "
"And to do so many experiments, Qin Yaoguang definitely can't just use her own egg cells." Lu Jin used a scientific tone to explain the general knowledge of egg cells to Gu Nianzhi.
"All mammalian females already have immature egg cells in their ovaries when they are born."
"The number of egg cells in female animals is fixed at birth. It won't increase, it will only gradually decrease."
"So Qin Yaoguang can't just use her own egg cells to conduct such a large number of experiments. She must have used other people's egg cells. "
Gu Nianzhi completely understood. She covered her mouth with her hand and gasped. "… Oh my god! How many embryo experiments did Qin Yaoguang do?! How many Wen Shouyi and Gu Nianzhi were born this way?! "
Lu Jin smiled bitterly. "Nianzhi, do you really think this kind of experiment is easy to succeed?"
"Do you think it's grafting seedlings?"
Gu Nianzhi: "…"
That was what she really thought!
"Could it be … more difficult?" Gu Nianzhi's thick, long eyelashes fluttered, and her big eyes were filled with curiosity.
"It's not more difficult, it's very difficult." Lu Jin didn't know how to explain it to Gu Nianzhi. "I just checked Wen Shouyi's DNA sequence. I can tell that Qin Yaoguang tried to genetically edit her, but she didn't succeed."
Gu Nianzhi frowned. "That means she started genetically editing the embryo before she gave birth to me, or was it for … He Zhichu's illness?"
"I don't know if she let Wen Shouyi give birth to He Zhichu's illness, but that might have been the prototype of her idea. From that time on, she started experimenting with this method. "
"But you have to know that the human gene is very complicated and huge. Decades ago, our understanding of genes wasn't as comprehensive as it is now, and our instruments and technical methods weren't as advanced as they are now. "
"Under those circumstances, the number of fertilized eggs that could successfully implant in an embryo experiment was very small. It could be said that only one in a thousand genetically edited fertilized eggs could successfully implant in the mother's body. "
"And after these fertilized eggs developed into embryos, it would be amazing if one in a hundred could successfully give birth."
Gu Nianzhi was very confused. "You mean, the pregnant embryos will miscarry?"
"Of course. And the chance of miscarriage is very high. " Lu Jin sighed. "Because these embryos have been genetically edited, many of them have genetic defects."
"And the human body has a self-selection function. Embryos with genetic defects are called congenital defects. In a natural state, they will miscarry unless you use unconventional methods to protect the fetus. "
"For scientific experiments, we don't protect embryos with congenital defects. Do you understand what I mean? There are very, very few children who have been successfully born and survived after genetic editing. I suspect that in Qin Yaoguang's experiments, Wen Shouyi was probably the only embryo that was born and survived. "
Gu Nianzhi nodded slowly. She understood a little, but she had new questions.
"… You said that the embryos that have been genetically edited have congenital genetic defects. Then … is it the same for Wen Shouyi and me?"
Lu Jin shook his head at first, then nodded. "You don't, but Wen Shouyi does."
Gu Nianzhi: "…"
"Why don't I have it?" Gu Nianzhi was very suspicious. "Dad, don't say that just to comfort me."
"I'm not comforting you. You're questioning my professional ability! "Lu Jin's eyes widened." … I personally did the gene editing! "
"My method is completely different from Qin Yaoguang's. She disrupted the order of the original gene fragments and only cultivated He Zhichu's defective genes. "
"I, on the other hand, eliminated the non-human virus genes on the basis of your original genes, and then used your own genes to expand the expression and supplement them."
"The result of this is that your genes haven't been changed, but have been optimized to the greatest extent on the original basis."
Lu Jin couldn't help but be smug. "The facts have proven that I've succeeded. You have the first perfect set of genes in human history! And it's on the basis that your original genes aren't changed! "
Gu Nianzhi: "_"
She started to stare at the mosquito coil again.
She knew every word that Lu Jin said, but she didn't understand it when they were put together.
※ ※ ※
This was the first update of the day: Chapter 1748, "Gene Optimization".
There were two updates today.
A reminder of everyone's monthly votes and recommendation votes.
Today was Monday, special recommendation votes!
Eight o 'clock in the evening, the second update.
Muah, all the big shots and little angels ~ ~ ~
You've already exceeded your reading limit for today. If you want to read more, please log in.
Login
Select text and click 'Report' to let us know about any bad translation.
